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The antibodies are produced by the patients own immune system resulting in an autoimmune reaction, which causes structural changes at the synapse. The disease is characterized by fluctuating weakness and easy fatigability of certain skeletal muscles. Patients may present with double vision or a drooping eyelid at the end of the day. Other facial muscles may be affected, resulting in difficulty in chewing, an abnormal smile, or nasal speech. In severe cases there may be difficulty in swallowing with the risk of aspirating food into the lungs and difficulty in breathing, due to weakness of the respiratory muscles, which can be life threatening if untreated.
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Authored by Dr. David A Gilpin
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The main route of excretion of drugs and drug metabolites is via the kidneys. Elimination varies amongst individuals and depends on the rate of metabolism of a particular drug, the rate of production of urine and the pH of urine.
02.09.2017
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Disorders of the CNS can be divided into psychiatric disorders and neurological disorders, although the distinction is not always clear. Psychiatric disorders include types of depression, schizophrenia, anxiety and insomnia and attention deficit hyperactivity disorder.
30.10.2020
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