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It is also formulated in combination with a sulphonamide, when it is known as co-trimoxazole, to treat pneumonia in patients with HIV. Due to the synergistic effect of the two drugs, this combination is more effective than either drug alone. Adverse effects on the production of blood cells occur with prolonged use of trimethoprim. The quinolones inhibit a bacterial enzyme, DNA gyrase.
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This occurs after many years of anti-psychotic drug use and is characterized by abnormal and disabling involuntary movements of the face, tongue, trunk and limbs. Phenothiazines have pronounced sedative effects. They are also antiemetic (due to the blocking of dopamine receptors in the chemotrigger zone) and cause increased levels of prolactin (by inhibition of the effects of dopamine in the hypothalamic-pituitary pathway, and women. This group of drugs is similar to phenothiazines with mode of action by block of dopamine D are very similar. An example from this group is flupenthixol. Side effects of thioxanthines are as expected, being antiemetic, Parkinsonism, tardive dyskinesia and raised prolactin levels.
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Guidelines on the management of chronic asthma and COPD are produced by the British Thoracic Society and published in the BNF and MIMS. Drugs used to treat other respiratory conditions are considered separately.
- Topical administration to the epidermis of the skin is generally used for drugs intended to have a local effect.
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- Because of this, broad-spectrum use of tetracyclines has declined and they are now used mainly to treat chlamydia infections, Lyme disease and acne.
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Treatment should be started as early as possible, when the first tingling sensation is felt. Side effects of topical use of acyclovir are transient stinging or burning of the skin.
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