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They may cause abdominal cramps. Examples of osmotic laxatives used prior to imaging are magnesium citrate and magnesium sulphate. Lactulose is a disaccharide with a similar action.
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The frequency of contrast agent injection and dose are known risk factors for renal toxicity. Ideally, in patients at high risk of renal toxicity, there should be five days between administrations and the lowest possible dose of either non-ionic monomer or non-ionic dimer should be used. Adverse reactions include the risk of acute renal failure due to blockage of tubules because contrast agents are relatively insoluble.
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PThey can have mucus viscosity and seeking expectoration. An example of a mucolytic is carbocisteine. Mucolytics should be used with caution in patients with a history of peptic ulcer because they may need the amount of blood in the stomach.
Authored by Douglas L Wood, MD
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