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Plasma protein binding therefore reduces active drug concentration and ultimate response to the drug. Drugs can compete for the same protein binding sites and this is a form of drug interaction. A well-known and important example is that of warfarin and aspirin. Warfarin is an anticoagulant, which binds extensively to plasma proteins, and this is taken into account when dosages are worked out. Aspirin taken with warfarin competes for the same protein binding sites, which means that they each displace the other and the amount of free drug in the plasma is increased for both drugs.

PSociety and College of Bacteria Nuclear Medicine Practice. Duplicate of Radiographers Prescribing for Radiographers: A View Paper. Society of Radiographers Role Disturbance Revisited: The Research Evidence. Westbrook, K.

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