Misoprostol can cause birth defects, premature birth, uterine rupture, miscarriage, or incomplete miscarriage and dangerous uterine bleeding. Do not use misoprostol if you are pregnant. If you are able to become pregnant, you will need to have a negative pregnancy test before starting this treatment. You will also need to use effective birth control to prevent pregnancy during treatment. Misoprostol reduces stomach acid and helps protect the stomach from damage that can be caused by taking a nonsteroidal anti-inflammatory drug NSAID such as aspirin, ibuprofen Advil, Motrin, naproxen Aleve, celecoxib, diclofenac, indomethacin, meloxicam, and others.

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Use: Reducing the risk of NSAID-induced gastric ulcers in patients at high risk of complications from gastric ulcers e. Use: Cervical ripening and labor induction in women with premature rupture of membranes. Use: Prevention of postpartum hemorrhage in settings where oxytocin is not available. Use: Treatment of early pregnancy loss, incomplete abortion, or missed abortion. Caution recommended. The risk of uterine rupture increased with advancing gestational ages and with prior uterine surgery, including cesarean delivery. In such patients, this drug may be prescribed IF the patient --Has a negative serum pregnancy test within 2 weeks prior to starting treatment. Safety and efficacy have not been established in patients younger than 18 years; this drug is not recommended for use in these patients.

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Cytotec may be used alone or with other medications. These are not all the possible side effects of Cytotec. Cytotec should not be used for reducing the risk of NSAID-induced ulcers in women of childbearing potential unless the patient is at high risk of complications from gastric ulcers associated with use of the NSAID, or is at high risk of misoprostol 100mcg gastric ulceration. In such patients, Cytotec may be prescribed if the patient. Cytotec oral tablets contain either mcg or mcg of misoprostol, a synthetic prostaglandin E 1 analog. Inactive ingredients of tablets are hydrogenated castor oil, hypromellose, microcrystalline cellulose, and sodium starch glycolate.

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It had no effect, compared to placebo, on gastrointestinal pain or discomfort associated with NSAID use. Adult and Pediatric Dosage. Pregnancy Termination. Stress Ulcer Prophylaxis off-label. Induction of Labor off-label. Not to be used in patients with previous cesarean delivery or major uterine surgery.

Adults: mcg P. Reduce dosage to mcg P. Adults: to mcg P. Pharmacodynamics Antiulcer action: Misoprostol enhances the production of gastric mucus and bicarbonate and decreases basal, nocturnal, and stimulated gastric acid secretion. Pharmacokinetics Absorption: Rapidly absorbed after oral use. The de-esterified metabolite undergoes further oxidation in several body tissues.

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Misoprostol, although originally introduced as a therapy for gastric ulcers, is now widely used in reproductive health. Previous Figure Next Figure.

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However, your doctor or pharmacist may have suggested a different schedule that is more appropriate misoprostol 100mcg you. Take it regularly and continuously to maintain its beneficial effects. Do not use more of this product, or more often, than prescribed. Avoid using or consuming substances that may irritate your stomach, such as It is preferable to take this medication with a meal or a snack in order to reduce side effects.

Treatment of intrauterine fetal death not accompanied by complete expulsion of products of conception in second and third trimesters of pregnancy. Renal impairment: Use with caution; peak plasma concentration, half-life, and bioavailability may be increased, but it is not clear whether these increases are of clinical relevance. Contraindicated in pregnant women to reduce peptic ulcer risk from nonsteroidal anti-inflammatory drugs NSAIDs. May cause diarrhea; should not be coadministered with other drugs that cause diarrhea eg, magnesium-containing antacids. Misoprostol may cause birth defects, abortion sometimes incomplete, premature labor or rupture of the uterus if given to pregnant women. Safety and efficacy in patients with cardiovascular disease, diabetes, renal impairment, or respiratory disease are not established.

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