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You should be able to answer these review questions from the material in this chapter. injection of drugs. and active transport of drug molecules across cell membranes. the gastrointestinal tract, its distribution around the body and its excretion by the kidneys. on drug excretion. barbiturates.
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Drugs have been developed following observation of side effects when being used for other purposes. As knowledge of receptor structures has developed, this has allowed drugs to be designed to fit with receptors.
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There is a major risk of malformation up to eight weeks post conception; therefore, drugs are best avoided for the first trimester of pregnancy.
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Mirtazapine enhances both noradrenergic and serotonergic transmission through block of pre-synaptic α-adrenergic receptors and Due to the blockade of drug does not produce the nausea associated with other serotonergic drugs. Mirtazapine does cause sedation and weight gain.
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