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There are many drugs in each group. The descriptions that follow are not intended to give a comprehensive account of all anti-cancer drugs available, rather to explain the modes of action and to give examples from each group. Toxic effects with all cytotoxic drugs are severe nausea and vomiting, hair loss and bone marrow depression.
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- In a small injury, this alone may be enough to stop the loss of blood.
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- Reference Department of Health Review of Prescribing, Supply and Administration of Medicines; Final report, Department of Health, London.
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Authored by Ron Simpson, MD
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In this way, trimethoprim interferes with the conversion of folate into its activated form, which is a cofactor in the synthesis of bacterial DNA. Dihydrofolate reductase also occurs in host cells, but it is less sensitive to trimethoprim.
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