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Assuming that Mrs Phillips does get pregnant later on and has to continue with antiepileptic medication, what special precautions could she take to help ensure she has a healthy baby. What is the advice on breast-feeding for mothers who take anticonvulsant medication. Case study Mr Warchowski is a medical history, you discover that he is being treated for a number of conditions. The patient was diagnosed with hypertension five years ago. He also has a history of depressive disorder, but it has been seven years since his last episode. Mr Warchowski has recently been diagnosed with benign enlargement of the prostate gland and is due to have suspected ischaemic heart disease investigated at the cardiology clinic.

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Levodopa, is the principle drug in this group. Replacement therapy with dopamine itself is not possible because it does not pass the blood-brain barrier.

  • This type of epilepsy is common in children.
  • Macrolides bind to the range of bacteria and are active orally.
  • The supplementary prescriber must ensure that the supplementary prescribing qualification is recorded on the HPC professional register and have access to continuing professional development thereafter.
  • Bipolar depression is associated with a decrease in dopamine activity and mania with an increase in dopamine activity.

Buscopan produces typical anticholinergic side effects of blurred vision, dry mouth, tachycardia and urinary retention. It should not be used in patients who have glaucoma or an enlarged prostate as it will make both of these conditions worse.

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The first two case studies are about hypothetical patients who might be seen in the podiatry clinic. However, other health care professionals might see similar patients for other reasons.

When the RAS is switched off sleep is possible. Acetylcholine, noradrenaline and serotonin all play a role in inducing sleep. GABA, dopamine and some neuropeptides influence sleep-inducing activity in cholinergic neurons. Insomnia is sleep disturbance and can be manifest as difficulty falling asleep, poor quality of sleep or premature awakening. Insomnia can be secondary to other conditions, for example anxiety or depression.

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These are neurotransmitters, which are stored in pre-synaptic glucophage prices in india. On release they cross the synaptic cleft and bind to receptors on the post-synaptic neuron. Binding of neurotransmitter with its receptor is very brief, but it brings about stimulation or inhibition of the post-synaptic neuron. See Figure transmission. The events that take place at a synapse, that is synthesis of neurotransmitter, storage in vesicles, release, interaction with receptors and eventual inactivation provide targets for drug action. Inactivation of a neurotransmitter can be by re-uptake into the neuron it was released from, or by the action of enzymes in the synaptic cleft.


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Griseofulvin should be taken with or after fatty food for adequate absorption.

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Since DMARDs are toxic and the course of rheumatoid arthritis can be unpredictable, their use may be delayed in order to ascertain that severe symptoms are persisting.

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