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The physiological functioning of this organ declines with age. At rate is approximately half that at age via the kidney are liable to accumulate in older patients. If these are drugs with a low TR, failure to excrete them at the expected rate may result in toxicity.
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- Reyes syndrome is a rare disorder of the liver and brain with a mortality rate of what role aspirin plays in its development.
- Most patients experience some relief from pain, stiffness and swelling, but these drugs do not alter the course of the disease, prevent tissue destruction or produce remission.
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Premedication is intended to prevent the parasympathetic effects of anaesthesia (excessive salivation and bronchial secretion and a reduction in heart rate) and to reduce anxiety or pain. Premedication and adjuncts to general anaesthesia are discussed further on page Induction is most likely to be achieved using an intravenous anaesthetic, which produces unconsciousness within seconds.
Authored by Dr. Shivani M Toma, MD
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Any disease that results in alteration in the pharmacokinetics of a drug will create these variations.
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Enterohepatic shunting describes the process whereby a drug is first metabolized and then excreted into the intestine via bile. Once in the intestine gut bacteria or intestinal enzymes convert the drug back to its original form, which is then reabsorbed.
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