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Neuraminidase inhibitors inhibit an enzyme, neuraminidase, that is produced by virus infected cells and which helps viruses to leave infected host cells. Zanamivir and oseltamivir are examples, which are used to treat influenza A and B in vulnerable individuals (those over renal disease, immunosuppression or diabetes).
- Resistance of bacteria to commonly-used antibiotics has become a major problem necessitating the development of new antibiotics.
- Most drugs are not developed or evaluated in children.
- They are effective in the late phase reaction and reduce the intensity of allergic reactions.
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Of aspects such as efficacy andor cost implications, and could therefore replace one medicine with another. If radiographers are using the old medicine as part of a PGD then that PGD would need urgent updating. An important aspect of medicines management is audit, because the Trust will monitor compliance with its policies and address deficiencies as required. In this respect, it is important that radiographers pay due attention to policies and comply as required with Trust governance. Radiographers, and other staff, should be adequately trained and educated in support of reducing risk to patients and also improving care and management (Society and College of Radiographers, to offer in-house training for those who wish to use PGDs and such courses are likely to include: stated outcomes; assessment that verifies the outcomes have been attained; remedial procedures for those who do not pass. The stated outcomes of PGDs are: Understand the concept of patient group directions Understand the historical and legal background to patient group directions Understand the meanings of pharmacodynamics and pharmacokinetics in relation to the drugs that the radiographer is able to supply and administer Understand the pathophysiological processes in the conditions under which the patient group directions can be used Understand the protocols and guidelines that exist to support the use of patient group directions.
Postgraduate certificate courses in Non-medical Prescribing for Health Care Professionals are run by many universities. Most courses are now interdisciplinary and allow training in supplementary prescribing and independent prescribing and enable supervised practice in different clinical settings as part of the course. For some, according to the Chartered Society of Physiotherapy, the ultimate goal is independent prescribing with physiotherapists taking responsibility for diagnosis and prescribing. This approach is not currently on the governments agenda. For this to become a reality, the profession needs to build a case for moving towards independent prescribing. Pharmacology would have to be incorporated into undergraduate programmes as it is in podiatry programmes.
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