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A year-old woman experienced a witnessed generalized seizure in the Emergency Department three hours after ingesting approximately mg of fluoxetine in a suicide attempt. Although the majority of fluoxetine ingestions are benign, seizures may occur after large intentional overdoses. The majority of fluoxetine overdoses result in a benign clinical course. We report the case of a witnessed, generalized seizure occurring three hours after a fluoxetine overdose in an otherwise healthy young woman. A year-old woman with a history of bulimia nervosa and depression ingested approximately seventy 20 mg fluoxetine capsules and 4—5 cans of beer in a self-professed suicide attempt. The patient stated that she had taken her buspirone only as directed, with the last dose on the morning of the fluoxetine overdose, about six hours earlier.
Effect of ethanol Adiantum capillus-veneris extract in experimental models of anxiety and depression. Monoamine aminotransferases, in particular, norepinephrine, serotonin, and dopamine, change in the brain of depressed people. Adiantum capillus-veneris is one of the species of the maidenhair fern genus that have traditionally been used to treat cough, cold symptoms, and local hair loss. In this experimental study, white male rats weighing g were assigned to 5 groups of 10 each; group 1: Receiving normal saline; groups Receiving A. Chronic unpredictable stress CUS was induced by 3-week exposure to chronic stress. The forced swim test and plus maze were used to assess depression and anxiety, respectively.
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Fluoxetine is a selective serotonin reuptake inhibitor SSRI antidepressant. Fluoxetine affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms. Fluoxetine is used to treat major depressive disorder, bulimia nervosa an eating disorder, obsessive-compulsive disorder, panic disorder, and premenstrual dysphoric disorder PMDD. This combination is also used to treat depression after at least 2 other medications have been tried without successful treatment of symptoms. You should not use fluoxetine if you also take pimozide or thioridazine, or if you are being treated with methylene blue injection. Do not use fluoxetine if you have used an MAO inhibitor in the past 14 days such as isocarboxazid, rasagiline, selegiline, phenelzine, or transcypromine.
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If you are experiencing or living with depression, your doctor may recommend an SSRI medication to help. SSRI, or selective serotonin reuptake inhibitor, drugs work by increasing the activity of serotonin in the brain. By increasing the level of serotonin, the medication can help balance feelings of mood and well-being. Zoloft sertraline and Prozac fluoxetine are two SSRI prescription drugs that can treat mental health conditions like depression, panic disorder, and obsessive compulsive disorder OCD. Although they are two of several different SSRI antidepressants, they have some similarities and differences.
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I tend to be an impulsive person. Coupled with my depression, it usually ends badly. Now, I am a year-old girl with a prescription for 40 mg fluoxetine daily. I've skipped taking it for the past couple days. I don't know. Now, this morning, for whatever reason I decided to take 4 capsules.
Fluoxetine is approved for the treatment of depression in children 8 years of age and older, and for the treatment of obsessive-compulsive disorder OCD in children 7 years of age and older. The safety and effectiveness of fluoxetine in younger children have not been established. In October, the FDA directed manufacturers of all antidepressants to include a boxed warning detailing the risk of suicide in pediatric patients. A causal role has been established for antidepressants in inducing suicidality in 2 mg clonidine patients. The clinical need for an antidepressant in children or young adults for any use must be weighed against the risk of increased suicidality; patients who are started on therapy should be observed closely for clinical worsening, suicidality, or unusual changes in behavior, particularly within the first few months of starting therapy or at the time of dose increase or decrease.
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Its molecular weight is The Pulvules also contain starch, gelatin, silicone, titanium dioxide, iron oxide, and other inactive ingredients. PROZAC monotherapy is not indicated for the treatment of depressive episodes associated with Bipolar I Disorder or the treatment of treatment resistant depression. Consider a dose increase after several weeks if insufficient clinical improvement is observed. As with other drugs effective in the treatment of Major Depressive Disorder, the full effect may be delayed until 4 weeks of treatment or longer.
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Discontinuing an antidepressant usually involves reducing your dose in increments, allowing two to six weeks or longer between dose reductions. Your clinician can instruct you in tapering your dose and prescribe the appropriate dosage pills.
- Dosing interval in hepatic impairment : Use with caution and monitor plasma levels and patient response.
- This antidepressant is in a class of drugs known as selective serotonin reuptake inhibitors, or SSRIs.
- There are several methods to define and calculate dose equivalence but for antidepressants, only daily defined dose and consensus methods have been applied to date.
- Common side effects include indigestion, trouble sleeping, sexual dysfunction, loss of appetite, dry mouth, rash, and abnormal dreams.
Eileen Brown, David L. Dunner, Susan L.
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Metrics details. Previous literature has found fluoxetine to be relatively safe in overdose.
Zoloft sertraline vs. Prozac fluoxetine : What's the difference? What are Zoloft and Prozac? Zoloft sertraline is a selective serotonin reuptake inhibitor SSRI type antidepressant used to treat depression, obsessive-compulsive disorder OCD, panic disorder, post-traumatic stress disorder PTSD, social anxiety disorder, and premenstrual dysphoric disorder PMDD. Depression may be caused by disturbances in the balance between serotonin and other neurotransmitters. Selective serotonin inhibitors block the reuptake of serotonin, therefore changing the level of serotonin in the brain.
Prozac fluoxetine is a popular medication used in the treatment of major depressive disorder, obsessive-compulsive disorder OCD, panic attacks, and some eating disorders. If taken as prescribed, the risk of Prozac overdose is low. If a person takes more than prescribed either accidentally or intentionally, however, an overdose is possible. Several factors—including age, weight, current state of health, and whether the person has also taken any other drugs along with Prozac—will determine whether any given dose will be harmful to an individual. This 200mg of fluoxetine it impossible to generalize about what particular dose would be considered to be an overdose.
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