NSAIDs relieve pain by reducing the production of prostaglandins, which are hormone-like substances that cause pain. Acetaminophen works on the parts of the brain that receive the pain messages. They can also cause kidney problems. These products include creams, lotions, or sprays that are applied to the skin in order to relieve pain from sore muscles and arthritis. Corticosteroids can be used to treat allergies, asthma and arthritis. Examples include: prednisone, prednisolone, and methylprednisolone. To minimize these potential side effects, corticosteroids are prescribed in the lowest dose possible for as short of a length of time as needed to relieve the pain.

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