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There is an increased risk of endometrial cancer in a woman with a uterus who uses unopposed estrogens. Estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman. It is a mixture of sodium estrone sulfate and sodium equilin sulfate. Tablets for oral administration are available in 0. Tablet strength Tablet color contains 0. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.
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