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After oral consumption, the estrogens are released gradually over the course of several hours. These estrogens help maintain healthy function of the endocrine system, offer relief from menopausal symptoms, and strengthen the bones, thereby helping to protect against osteoporosis. One of the most common Premarin uses involves the management of menopausal symptoms that result from the ovaries' natural decline in estrogen production.

Premarin may also be prescribed to people who have low estrogen levels for reasons other than menopause. For instance, it may be prescribed to people who have had a hysterectomy, which involves the removal of a person's ovaries. When a person's ovaries are removed, their estrogen levels drop, and they may deal with the same symptoms associated with menopause. Additionally, Premarin may be used to help prevent osteoporosis, an issue often tied to estrogen decline. When estrogen levels drop, bones may become thinner and weaker and therefore more susceptible to osteoporosis.

Supplementing with estrogen may prevent these issues. Tell your doctor about any medical conditions you have or any medications or supplements you take. This will help ensure that Premarin doesn't adversely interact with these conditions or medications. While taking Premarin, make sure to conduct regular self-exams of your breasts and see your doctor regularly for physical exams. If at all possible, avoid smoking cigarettes while using Premarin, as smoking can increase the risk of blood clots, heart attack, or stroke while using this medication.

If you miss a dose and it's not near the time for your next dose, take the dose as soon as you remember. If it's near the time for your next dose, take the missed dose as soon as you can, but skip it if it's almost time for your next dose. Do not take two doses at one time. Be aware that grapefruit and products containing grapefruit juice may interact with Premarin and increase the risk of side effects. Premarin is derived from the urine of pregnant mares, and the ethics of these practices are a matter of debate.

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