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The middle and thickest layer of the cortex produces glucocorticosteroids, the main one being cortisol. Secretion of cortisol is mediated through feedback pathways involving adrenocorticotrophic hormone from the anterior pituitary and corticotrophin releasing hormone from the hypothalamus as well as stimulation from higher brain centres.
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Once bound, the viral RNA enters the cell and using the cells components makes a DNA copy of itself by reverse transcription. The newly formed DNA then inserts itself into the host DNA.
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