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Management of pain or neuropathic pain associated with diabetic peripheral neuropathy DPN severe enough to require daily, around-the-clock, long-term analgesia for which alternative treatment options are inadequate. Not for use as an as-needed prn analgesic. Use only if alternative treatment options eg, non-opioid analgesics, immediate-release opioids are ineffective, not tolerated, or otherwise inadequate to provide sufficient management of pain. Use lowest effective dose for shortest duration. Swallow whole.

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