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- PTricyclic antidepressants should be expected with caution in patients with liver inhalation.
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Response to drugs varies between individuals and although the reasons are often multifactorial there are cases where gene polymorphism is responsible.
01.05.2016
Egon
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GABA receptors are found on chloride ion channels at inhibitory synapses in the CNS, including the RAS (see Figure When chloride channels open, chloride ions flow inwards making the neuronal membrane hyperpolarized. This means that there is a reduction in impulses passing on to other parts of the brain and this effect normally produces a reduction in anxiety and wakefulness.
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