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The intervals should be no longer than one year apart and more frequent if antibiotics are included in the CMP. The independent prescriber may, at any time, review the patient andor resume full responsibility for their care.
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The site of decarboxylation of levodopa in patients with Parkinsons disease is uncertain, but it may be that there is sufficient enzyme in the remaining dopamine nerve terminals or that conversion takes place in other neurons as they also contain decarboxylase enzymes. Release of dopamine replaced in this way must be very abnormal but most patients seem to benefit.
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