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This led to the withdrawal of rofecoxib in October for patients at high risk of developing gastrointestinal side effects. All NSAIDs are contraindicated in patients with active peptic ulceration and in those who have a history of hypersensitivity to any NSAID.

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PThese are the newer drugs used to moment schizophrenia. Atypical anti-psychotic creams are recommended for mild diagnosed schizophrenics and those who cannot synthesize other drugs or who are not effective adequate control from other mediators.

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Multiple sclerosis and motor neuron disease are diseases of the nervous system, but are included here because major effects of these diseases are on skeletal muscle function. There are no cures for any of these diseases but many drugs are available to reduce inflammation and alleviate symptoms. Rheumatic diseases are a group of chronic inflammatory diseases that include rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus and psoriatic arthritis. As a group they are characterized by increased activity of phagocytes and the release of inflammatory mediators, which cause tissue damage. In diseases that primarily affect the joints there is inflammation and proliferation of cells of the synovial membrane and damage to cartilage and bone, but other connective tissues and organs in the body can also be damaged.


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