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Known teratogens include alcohol, anticancer drugs, warfarin, anticonvulsants and tetracyclines. Carcinogenesis is the occurrence of drug-induced tumours. This can happen through damage to DNA causing mutation of genes, activation of proto-oncogenes or damage to oncogene suppressors. Due to strict testing of new drugs during the developmental stages this should be a rare phenomenon. However, some drugs through immunosuppression, are known to increase the risk of tumour formation. For example, drugs used to treat cancers and drugs used to prevent transplant rejection are known to do this.
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Intravenous Urography injection of contrast agents by radiographers. Clinical Radiography, Medicines Regulations Administration of Radioactive Substances. The Medicines for Human Use Miscellaneous Amendments Order No Office of Sector Information Medicinal Products Prescription by Nurses etc. Act, HMSO, London. Price, R. and Le Masurier, S.
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Colchicine interferes with the formation of tubulin necessary for cell division and cell motility and as such inhibits the formation and migration of leukocytes into the inflamed joint. It is not, however, useful for other types of inflammation.
- This is because of their adverse effects in raising blood glucose levels.
- Osteomalacia is a deficiency disease.
- It is a condition in which there is loss of spinal motor neurons and neurons of descending motor pathways from pyramidal cells of the cerebral cortex.
- In a small injury, this alone may be enough to stop the loss of blood.
- Vitamin K can be used to counteract the effects of warfarin in the event of excessive bleeding.
- A mixture of soluble (rapid and short duration of action) and isophane human insulin twice a day is the most commonly used regime.
- Long-term treatment with drugs that control uric acid levels prevents future episodes of gout and helps resolve tophi.
Involvement of weight-bearing joints is the greatest cause of disability in older people. Osteoarthritis is primarily a degenerative disease of cartilage.
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Assuming you have advised Pete to make an appointment with his doctor to review his medication, when you next see him he tells you the doctor has increased the dose and told Pete to give the drug more time to have an effect. Given the increase in dose, what are the side effects Pete might experience.
There are so many antibiotics it is helpful to consider them in groups according to their mode of action. Examples are given for each major group. The sulphonamides were the first drugs found to be effective in the treatment of systemic infections and although they do still have some specific uses, for example treatment of toxoplasma infections in patients with HIV, they are not much used nowadays because of bacterial resistance and the development of more effective drugs, which are less toxic. Silver sulfadiazine is used topically to treat infected wounds ( Sulphonamides inhibit an enzyme, dihydropteroate synthatase, used in the production of folic acid in many bacterial cells. Folic acid is the starting point for a cofactor necessary for DNA synthesis in both bacterial and human cells.
Tolerance and dependence are not usually a problem in clinical use. Other opioid analgesics are compared to morphine Neuropathic pain is severe chronic pain due to damage to sensory nerves. This is not because of tissue injury and can occur as a consequence of central nervous system disorders, such as stroke or multiple sclerosis, or because of malignancy, amputation (phantom limb pain) diabetic neuropathy or following infection with Herpes zoster. Mechanisms underlying neuropathic pain are poorly understood. The pain is described as burning, shooting or scalding pain and it can be difficult to treat with conventional analgesics. Often a combination of physiotherapy and psychological treatment together with one or more of the following approaches is needed.
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Not all epileptic seizures can be controlled by conventional therapy, and so new drugs have and are being developed. Some of them already in use are discussed below.
21.04.2017
Martha
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The role of the podiatric surgeon is to provide specialist management of foot pathology by surgery and alternative measures, either directly or by referral to podiatrists or other healthcare professionals.
12.12.2016
Heinrich
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A number of drugs are used as adjuncts to radiography. They can be administered by qualified, registered and trained radiographers under patient group directions.
11.03.2016
Therese
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Some drugs, for example phenytoin, oral contraceptives and isoniazid, can cause reduced absorption of folic acid. Oral replacement therapy with folic acid is effective.
08.07.2018
Stefan
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Because podiatrists are likely to be treating fungal infections of the feet, some prescription-only antifungal drugs have been added to the list of exemptions for qualified podiatrists registered with the Health Professions Council. The first three of the following drugs are available in many preparations as over-thecounter medicines.
23.03.2018
Luca
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