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Clinical uses include treatment of acute myocardial infarction, pulmonary embolism and peripheral thromboembolism and in the restoration of circulation through arterial grafts and intravenous catheters. Examples are streptokinase and alteplase. Streptokinase is naturally produced by streptococcal bacteria whereas alteplase is recombinant tissue plasminogen activator.
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All drugs in this group inhibit liver enzymes and cause interactions with many other drugs. In particular, they increase the risk of myopathy with statins. Some antiviral drugs in this group act by blocking an ion channel that allows the release of genetic material from viruses once they are inside the host cell and which allows viral particles to leave the infected host cell to infect other cells.
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There are likely to be many nurses, pharmacists and other health care professionals who meet the criteria for training to become supplementary prescribers. The four key principles that should be used to prioritize potential applicants are: access to medicines for them; All health care professionals who are involved with supplementary prescribing will require continuing professional development. Practitioners have a responsibility to keep themselves up to date with clinical and professional developments. Since for Continuing Professional Development of the Health Professions Council. This is a self-declaration, which has to be kept current with practice within an individuals practice.
Act, HMSO, London. Price, R. and Le Masurier, S. Longitudinal changes in extended roles in radiography: a new perspective.
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