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Valtrex is indicated for the treatment of herpes zoster shingles and ophthalmic zoster in immunocompetent adults see sections 4. Valtrex is indicated for the treatment of herpes zoster in adult patients with mild or moderate immunosuppression see section 4. Clinical studies have not been conducted in HSV-infected patients immunocompromised for other causes than HIV-infection see section 5. Varicella zoster virus VZV infections — herpes zoster and ophthalmic zoster. Patients should be advised to start treatment as soon as possible after a diagnosis of herpes zoster. There are no data on treatment started more than 72 hours after onset of the zoster rash.
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While many scientists are working on developing a coronavirus vaccine, others are busy testing antiviral drugs. How do antiviral drugs work? These drugs are known as RNA-polymerase inhibitors. These types of drugs have successfully cured people of chronic hepatitis C — another RNA virus infection. But not all viral RNA polymerases are the same, so the drugs that work for hepatitis C virus will not necessarily work for human coronaviruses. Favilavir is an RNA polymerase inhibitor drug scientists are currently trialling against coronavirus. The presence of these analogues in the viral genome blocks the viral polymerase, meaning the virus cannot make another copy of its RNA.
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It is prescribed to adults and children over two years of age to treat or prevent such viral diseases, as herpes or chicken pox. The use of Valtrex in high doses is not recommended for geriatric patients, patients with impaired CNS function or kidney diseases.
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The partners with HSV-2 infection were randomly assigned to receive either mg of valacyclovir once daily or placebo for eight months. The susceptible partner was evaluated monthly for clinical signs and symptoms of genital herpes.
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An outline of normal physiology of the systems is included where appropriate and relevant diseases described briefly. This is not intended to be a physiology book or a pathophysiology book. Should the reader need to consult such books, suggestions are given in the bibliography. Major groups of drugs are discussed, with emphasis on areas of relevance to the three professions for whom the book is intended. In addition to drugs used to treat diseases of the major systems, the treatment of infections and parasites, the use of cancer chemotherapy, the use of anaesthetics and analgesics and the use of contrast agents and adjuncts to radiotherapy are included in Part The final part has two chapters. The first of the two is about legislation around the use of medicines with discussion of salient points from the Medicines Act patient group directions, supplementary prescribing and independent prescribing and a brief history of non-medical prescribing are considered.
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